by Katie McCormack, MD
Allergy & Immunology at Boulder Medical Center
Xolair: A Game-Changer in Food Allergy Treatment
Xolair, also known as Omalizumab, is creating a buzz in the food allergy community as the first FDA-approved medication to reduce allergic reactions caused by accidental exposure to multiple food triggers.
On February 16, 2024, the FDA approved Xolair for food-allergic patients ages one year and above. This drug does not cure food allergies, unfortunately, as there is no known cure for these conditions. Instead, it is designed to help reduce the chance of severe reactions like anaphylaxis in case of accidental ingestion of the allergen.
Xolair is a type of medication called a monoclonal antibody and has been used for other allergic conditions for over 20 years. It works by binding to the IgE antibody and blocking the antibodies’ ability to bind to its receptors responsible for triggering allergic reaction symptoms.
Xolair can help treat IgE-mediated food allergies, which have the potential to trigger anaphylaxis. It is ineffective for other types of food allergies, such as FPIES or EoE. It is also worth noting that Xolair is not food-specific, which means it can reduce the risk of severe reactions regardless of the type of food the patient is allergic to. Additionally, it can help reduce the risk of severe reactions even if the patient has multiple food allergies.
Xolair should be taken regularly to provide benefits. It is administered via injection every two or four weeks, and the dosage will depend on the patient’s weight and total Immunoglobulin E (IgE) level. Please note that Xolair is not an emergency medication for treating severe allergic reactions. Epinephrine should always be available.
Consultation and Next Steps
Allergists are familiar with this drug and can help you learn more about it. If you think Xolair could be right for you, please schedule a visit with our allergy team to learn more.
Resources
Katherine McCormack, MD
Asthma, Allergy, and Immunology in Louisville, Colorado
Dr. Katie McCormack is a board-certified allergy specialist. She evaluates and treats infants, youth, and adults for various allergy conditions, including seasonal and food allergies. Dr. McCormack welcomes new patients to her clinic in Louisville, Colo.
- Dr. McCormack’s Full Profile.
- Call (303) 440-3083 for an appointment